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At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- "J of the International Society of Sports Medicine"; International Society of Sports Nutrition Position Stand; E.R. Goldstein, et al.; Jan 27, 2010
- "J of the International Society of Sports Medicine"; International Society of Sports Nutrition Position Stand; E.R. Goldstein, et al.; Jan 27, 2010
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What Is Anhydrous Caffeine?
Anhydrous caffeine is caffeine that contains lower amounts of water. Anhydrous caffeine contains 0.5 percent or less water, while hydrous caffeine contains up to 8.5 percent water. The powder is only slightly soluble in water. It is a dry, odorless, white crystalline product with a bitter taste.
Weight Loss Products
The dry powder can be further compressed into pellets or granules, and is used for its stimulant effect in tablets, capsules and drinks. Anhydrous caffeine is a commonly and conveniently added ingredient to commercial weight loss pills. It is also added to energy drinks that are designed to promote your mental and physical performance. Caffeine can affect you in this way if you take it in moderate doses between 3 to 6 milligrams per kilogram, or 2.2 lbs, of your body weight.
- The dry powder can be further compressed into pellets or granules, and is used for its stimulant effect in tablets, capsules and drinks.
How It Works
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Caffeine, most of which is extracted from natural sources, is considered a mild nervous system stimulant that can be habit-forming. It is not an addictive substance, however. Young people and smaller individuals may be more sensitive to its effects. Studies involving athletes indicate that you would probably get a bigger boost of energy from taking anhydrous caffeine than drinking coffee, especially for high-intensity or maximal endurance exercise.
- Caffeine, most of which is extracted from natural sources, is considered a mild nervous system stimulant that can be habit-forming.
Extraction
Caffeine is extracted from tea leaves and poor quality coffee beans. It is also a by-product of decaffeinating coffee beans. Decaffeination is accomplished either by using carbon dioxide or very hot water. Since natural sources are in plentiful supply, there is no need to synthesize caffeine, a process which costs more than extraction3. Because pure caffeine is toxic, suppliers may not sell it to individual purchasers. The lethal dose for adults is thought to be 10 grams or 0.35 ounces.
- Caffeine is extracted from tea leaves and poor quality coffee beans.
- Because pure caffeine is toxic, suppliers may not sell it to individual purchasers.
Overdose
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Despite the toxicity of caffeine, there are not many people who are known to have died from caffeine poisoning3. Swallowing or inhaling the powder can cause an overdose. Symptoms of overdose include:
- nausea
- vomiting
- stomach pain
- headache
- dizziness
- rapid pulse
- low blood pressure
- insomnia
- convulsions
- 呼吸急促(气促)
- collapse
High doses of caffeine would cause you to start vomiting long before levels in your blood became too high.
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References
- "Handbook of Fillers, Extenders, and Diluents"; Irene Ash; 2007
- "Food Chemicals Codex"; 2003
- "J of the International Society of Sports Medicine"; International Society of Sports Nutrition Position Stand; E.R. Goldstein, et al.; Jan 27, 2010
- "13th International Workshop on Industrial Crystallization"; Peter Jansens, et al.; 2006
- "Crystalline Caffeine"; Simon Tilling; 2001
- U.S. National Library of Medicine, MedlinePlus. Caffeine. Updated April 30, 2019.
- U.S. Food and Drug Administration. Pure and highly concentrated caffeine. Updated September 21, 2018.
- U.S. Department of Defense Dietary Supplement Resource. Caffeine: different names, different forms. Updated February 26, 2019.
- Parikka V, Beck J, Zhai Q, Leppäsalo J, Lehtonen L, Soukka H. The effect of caffeine citrate on neural breathing pattern in preterm infants. Early Hum Dev. 2015;91(10):565-568. doi:10.1016/j.earlhumdev.2015.06.007
- U.S. National Library of Medicine, National Center for Biotechnology Information, PubChem Database. Caffeine (CID 2519).
- Grgic J, Grgic I, Pickering C, Schoenfeld BJ, Bishop DJ, Pedisic Z. Wake up and smell the coffee: caffeine supplementation and exercise performance-an umbrella review of 21 published meta-analyses. Br J Sports Med. 2019. doi:10.1136/bjsports-2018-100278
- 霍奇森AB, Randell RK, Jeukendrup AE. The metabolic and performance effects of caffeine compared to coffee during endurance exercise. PLoS ONE. 2013;8(4):e59561. doi:10.1371/journal.pone.0059561
- Trexler ET, Smith-Ryan AE, Roelofs EJ, Hirsch KR, Mock MG. Effects of coffee and caffeine anhydrous on strength and sprint performance. Eur J Sport Sci. 2016;16(6):702–710. doi:10.1080/17461391.2015.1085097
- NCAA, Sports Science Institute. 2019-2020 NCAA banned substances.
- World Anti-Doping Agency. 2020 List of Prohibited Substances and Methods. Updated January 1, 2020.
- World Anti-Doping Agency. 2020 Monitoring Program. Updated January 1, 2020.
- European Food Safety Authority. Scientific opinion on the safety of caffeine. EFSA Journal. 2015;13(5):4102
- Willson C. The clinical toxicology of caffeine: A review and case study. Toxicol Rep. 2018;5:1140–1152. doi:10.1016/j.toxrep.2018.11.002
- U.S. National Library of Medicine, MedlinePlus. Caffeine in the diet. Updated April 30, 2019.
- Grgic J, Trexler ET, Lazinica B, Pedisic Z. Effects of caffeine intake on muscle strength and power: a systematic review and meta-analysis. J Int Soc Sports Nut. 2018;15:11. doi:10.1186/s12970-018-0216-0
- U.S. Food and Drug Administration. Warning letter: smartpowders. August 27, 2015.
- Wickham KA, Spriet LL. Administration of caffeine in alternate forms. Sports Med. 2018;48(Suppl 1):79-91. doi:10.1007/s40279-017-0848-2
Writer Bio
Lexa w·李是一个新的Orleans-based作家与铁道部e than 20 years of experience. She has contributed to "Central Nervous System News" and the "Journal of Naturopathic Medicine," as well as several online publications. Lee holds a Bachelor of Science in biology from Reed College, a naturopathic medical degree from the National College of Naturopathic Medicine and served as a postdoctoral researcher in immunology.